Tumours and Gonadotrophin Deficiency (2) The most common of such tumours are craniopharyngiomas and germinomas. Other tumours in the hypothalamopituitary area include hypothalamic or optic gliomas or astrocytomas. Chromophobe adenomas are rare in childhood compared to their frequency in adulthood, but are reported. See later: • Craniopharyngioma in Puberty • Germinomas in Puberty See also: • Hypopituitarism